İpek Şehri nde Nüfus ve Yerleşim (1485-1582)
نویسندگان
چکیده
منابع مشابه
10 Chapter 1582
The hard-shell capsule is a commonly used dosage form, and it has been estimated that approximately 60 billion capsule shells are used annually for pharmaceutical products (Podczeck, 2004). The product essentially consists of a hard shell, usually gelatin based, that is almost always filled with a particulate solid. Among the advantages claimed for the hard-shell capsule compared with tablets a...
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Stem cells ensure tissue homeostasis through the production of differentiating and self-renewing progeny. In some tissues, this is achieved by the function of a definitive stem cell niche. However, the mechanisms that operate in mouse spermatogenesis are unknown because undifferentiated spermatogonia (Aundiff ) are motile and intermingle with differentiating cells in an ‘open’ niche environment...
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Tegafur (FT), a prodrug of 5-fluorouracil, is a chiral molecule, a racemate of Rand S-isomers, and CYP2A6 plays an important role in the enantioselective metabolism of FT in human liver microsomes (R-FT >> S-FT). This study examined the enantioselective metabolism of FT by microsomes prepared from Sf9 cells expressing wildtype CYP2A6 and its variants (CYP2A6*7, *8, *10, and *11) that are highly...
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Double minutes (dmin), the cytogenetic hallmark of genomic amplification, are found in 1% of karyotypically abnormal acute myeloid leukemias (AML) and myelodysplastic syndromes (MDS). The MYC gene at 8q24 has been reported to be amplified in the majority of the cases, and generally it has been assumed that MYC is the target gene. However, only a few studies have focused on the extent of the amp...
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The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share specific substrates. Mib1 is known to play essential roles in Notch signalling by ubiquitinating Notch ligands in vivo. Conversely, the functions of Mib2 in vivo are not fully understood, although Mib2 ubiquitinates multiple substrates, including Notch ligands, in vitro...
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ژورنال
عنوان ژورنال: History Studies International Journal of History
سال: 2020
ISSN: 1309-4688
DOI: 10.9737/hist.2020.849